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Can negotiating with America help to alleviate the problems facing Iran?

And what proof and evidence is there that negotiating with America leads to losses?

What is a concise summary of the JCPOA?

And what does it mean if one were to try to negotiate with America in the present-day, despite past experiences?

The Leader of the Muslim Ummah, Imam Sayyid Ali Khamenei, talks about \\\"Negotiations With America!?\\\".